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د. محمد مصطفى محمد كمال


نبذه عن


• 2001, graduated from Faculty of Pharmacy, Ain Shams University with Excellence with Honor. • 2001-2007, I worked as teaching assistant in Biochemistry Department, Faculty of Pharmacy, Ain Shams University then, I got my Master’s degree in 2006 on diabetic cardiovascular complications. • 2011, I got my Ph.D. on glioblastoma cancer stem cells where I joined Sadhan Majumder's lab in Genetics Department, M.D. Anderson Cancer Center, Houston, Texas, USA from 2008 through 2010 as part of Joint Supervision scholarship from Egyptian Government. • 2014, I managed to get a Fulbright postdoctoral fellowship for nine months in M.D. Anderson Cancer Center, doing more research on brain tumor. • 2017, I go promoted to Associate Professor and joined Faculty of Pharmacy, the British University in Egypt as Associate Professor of Biochemistry on secondment. • November 2019 till May 2023, Director of the Center for Drug Research and Development (CDRD), Faculty of Pharmacy, The British University in Egypt. • May 2023 till current, Drug Research and Development Group Leader, under the Health Science Center of Excellence, The British University in Egypt. • I have 26 publications in Scopus indexed journals with decent impact factors and h-index 12, almost 430 citations as of October 2023, in addition, to a book chapter. • Also, I have participated in many national and international conferences, supervised a lot of Master and Ph.D. theses and undergraduate graduation projects in Ain Shams University, Cairo University, Suez Canal University and The British University in Egypt. Research interests I. Stem cell biology After my Ph.D., I returned home to Egypt, where I established a stem cell line of research in 2 universities. We managed to isolate mesenchymal stem cells (MSCs) from umbilical cord (in Ain Shams University) and adipose tissue (in The British University in Egypt). We are interested in the isolation of mesenchymal stem cells from different sources including umbilical cord, bone marrow and adipose tissue. Consequently, we are examining the differentiation of these cells into different lineages with special interest in the differentiation of mesenchymal stem cells into insulin producing cells for diabetes treatment and osteocytes for bone disease therapy. Our overall aim is to study how to improve the differentiation of mesenchymal stem cell into other cell types both in-vitro and in-vivo for better cell therapy outcomes of different diseases. II. β-cell dysfunction and Single nucleotide polymorphisms (SNPs) in diabetes mellitus (DM) We are interested in studying the β-cell dysfunction as a major determinant of type 1 and type 2 diabetes mellitus. We tried to measure some biochemical markers that closely reflect the β-cell function to be used as clinical markers of β-cell status in diabetic patients of different types of diabetes. In addition, we are examining the association of SNPs of various players in DM and their association with developing DM, glycemic control and/or diabetes complications. III. Cancer The other discipline we are working on is Cancer, especially cancer stem cells. Having my training in M.D. Anderson Cancer Centre Genetic Department through my Ph.D. and Fulbright postdoctoral fellowship, I was trained on studying these cells. Currently, we are working on cancer stem cells isolated from breast cancer cell lines and study some target genes. Also, we are isolating exosomes from colon rectal cancer (CRC) patients’ serum and study their diagnostic and prognostic roles in CRC. Scopus profile https://www.scopus.com/authid/detail.uri?authorId=56978730400 Google scholar profile https://scholar.google.com/citations?user=1daGrI8AAAAJ&hl=en
  • الكلية: كلية الصيدلة
  • القسم: قسم الكيمياء الحيوية
  • التخصص العام : علوم صيدلية تخصص كيمياء حيوية
  • التخصص الدقيق: كيمياء حيوية وبيولوجيا جزيئية (خلايا جذعية ومرض السكري)
  • الدرجة الوظيفية: استاذ مساعد
  • الحالة: معار
  • البريد الالكتروني الرسمي: mohamed_kamal@pharma.asu.edu.eg
  • Google Scholar: Google Scholar Link
  • Research Gate: Research Gate Link
  • Scopus: Scopus Link
  • H-index: 8
  • Orcid: https://orcid.org/0000-0002-6004-2590
  • Research Fields: Glioblastoma Stem Cells,Oncogenic Properties, Diabetes, Stem cells, Genetics, SNPs
  • السيرة الذاتية: تحميل السيرة الذاتية

إحصائياتي


بوابة البحث العلمي
39

الاقتباسات
828

الجوائز
1

الاقتباسات


التعليم

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التدرج الوظيفي

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ورش العمل

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المؤتمرات العلمية

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الجوائز

  • 2017

    الجائزة: جوائز من الجامعة لنشر أبحاث بمجلات عالمية

    • مقدم الجائزة: جامعة عين شمس
    • تصنيف الجائزة: الجوائز العلمية المتنوعة

بوابة البحث العلمي (39)

عنوان البحثالسنةالاقتباسات
The effect of diabetes mellitus on differentiation of mesenchymal stem cells into insulin-producing cells 2024
Revealing the role of serum exosomal novel long non-coding RNA NAMPT-AS as a promising diagnostic/prognostic biomarker in colorectal cancer patients 2024 3
Adipose-Derived Mesenchymal Stem Cells and Their Derived Epidermal Progenitor Cells Conditioned Media Ameliorate Skin Aging in Rats 2024 1
Silencing of forkhead box protein O-1 (FOXO-1) enhances insulin-producing cell generation from adipose mesenchymal stem cells for diabetes therapy 2024 1
Adipose Mesenchymal Stem Cells in Skin Aging 2023
Elafibranor modulates ileal macrophage polarization to restore intestinal integrity in NASH: Potential crosstalk between ileal IL-10/STAT3 and hepatic TLR4/NF-κB axes 2023 14
Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 inflammasome 2022 43
Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players 2022 61
Isolation of rat adipose tissue mesenchymal stem cells for differentiation into insulin-producing cells 2022 8
Sources and therapeutic strategies of mesenchymal stem cells in regenerative medicine 2022 24
Exendin‐4 enhances osteogenic differentiation of adipose tissue mesenchymal stem cells through the receptor activator of nuclear factor‐kappa B and osteoprotegerin signaling … 2022 13
Exendin-4 enhances osteogenic differentiation of adipose tissue mesenchymal stem cells through rank/rankl/opg axis 2021
Nampt/visfatin: a new player to consider for the differentiation of mesenchymal stem cells into insulin producing cells 2021
New emerging roles of the novel hepatokine SERPINB1 in type 2 diabetes mellitus: Crosstalk with β-cell dysfunction and dyslipidemia 2021 11
The regenerative potential of mesenchymal stem cells for diabetes mellitus–several weapons and one aim 2021

اسم المجلةتاريخ النشرالقطاعالموقع الإلكتروني للمجلةISSN
Journal of cellular Biochemistry2022-03-26طبي الموقع الإلكتروني للمجلة1097-4644
Inflammopharmacology2022-04-01طبي الموقع الإلكتروني للمجلة1568-5608
Biomedicine & Pharmacotherapy2022-11-30طبي الموقع الإلكتروني للمجلة1950-6007
Biological Research2024-05-02العلوم الأساسية الموقع الإلكتروني للمجلة0716-9760
Tissue Engineering and Regenerative Medicine2024-06-24العلوم الأساسية الموقع الإلكتروني للمجلة1738-2696
Molecular and Cellular Biochemistry2024-10-26العلوم الأساسية الموقع الإلكتروني للمجلة0300-8177
Future Journal of Pharmaceutical Sciences2024-11-08طبي الموقع الإلكتروني للمجلة2314-7245
Life Sciences2022-01-21طبي الموقع الإلكتروني للمجلة0024-3205
Journal of Visualized Experiments2022-08-29طبي الموقع الإلكتروني للمجلة1940-087X
Life Sciences2024-06-29طبي الموقع الإلكتروني للمجلة0024-3205
Life Sciences2024-03-26طبي الموقع الإلكتروني للمجلة0024-3205
Trends in cell biology2024-12-24طبي الموقع الإلكتروني للمجلة0962-8924

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اسم الكتابتاريخ النشرالقطاعالموقع الإلكتروني للكتابISBN
Handbook of Stem Cell Therapy2022-02-10طبي الموقع الإلكتروني للكتاب978-9-81-166016-0

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الجوائز المرشح لها

  • 2023

    الجائزة: جائزة الأستاذ الدكتور إكرام عبد السلام في مجال الوراثة الطبية

    • مقدم الجائزة: كلية الطب جامعة القاهرة
    • مجال الجائزة: الوراثة الطبية
    • تصنيف الجائزة: الجوائز العلمية المتنوعة

الإنجازات العلمية

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